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200. MM Pharm Introduction to Laboratory Research
(4-6 units). Individual
projects in laboratory research for beginning graduate students.
At end of each term students submit to their supervisor a report
covering research performed. Pharmacology graduate students must
take this course three times during their first two years in residence.
S/U or letter grading. (Fall, Winter, Spring)
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M200A/B. Neurobiology (6 units). Same as Molecular,
Cell, and Developmental Biology CM220. Lecture two hours;
discussion two hours. Lecture two hours; discussion two hours; laboratory
two hours. Fundamental topics concerning molecular, cellular, and
developmental neurobiology, including intracellular signaling, cell-cell
communication, neurogenesis and migration, synapse formation and
elimination, programmed neuronal death and neurotopic factors. Letter
grading. (Fall - B; Winter - A).
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M229. MCDB Cellular Biology of Host/Pathogen Interactions
(6 units). Same as MIMG M229.
Lecture four hours; discussion ninety minutes. Requisite: Biological
Chemistry CM253. Molecular and cellular biology of pathogens,
eukaryotic host cells, and interaction between pathogens and hosts.
Letter grading.
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237. MM Pharm Research Frontiers in Cellular and Molecular
Pharmacology (4-8 units). Detailed
examination of principles of pharmacology and mechanisms of drug
action at organismal, tissue, cellular, and molecular levels, with
emphasis on receptors, receptor/effector coupling, neurotransmitters,
cardiovascular pharmacology, autonomic and central nervous system
pharmacology. S/U or letter grading. (Fall)
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M241. MM Pharm Introduction to Chemical Pharmacology and
Toxicology (6 units). Same as Mol Tox M241. Preparation:
organic and biological chemistry. Introduction to general principles
of pharmacology. Role of chemical properties of drugs in their distribution,
metabolism, excretion and modes of action. (Spring)
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CM248. Biol Chem Molecular Genetics (Concurrent
with CM253). Molecular genetics of four systems:
bacteria, yeast, Drosophila and mouse/humans. Letter Grade(Fall)
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M248. MM Pharm Introduction to Biological Imaging (4
units). Same as Biomedical Physics M248.
Lecture three hours; laboratory one hour; outside study,
seven hours. Exploration of role of biological imaging in modern
biology and medicine, including imaging physics, instrumentation,
image processing, and applications of imaging for a range of modalities.
Practical experience provided through a series of imaging laboratories.
Letter grading. (Winter)
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251. MM Pharm Seminar: Pharmacology (2
units). Seminars presented by guest lecturers, faculty
and students, on a variety of topics. S/U grading. (Fall, Winter,
Spring)
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CM253. Biol Chem Macromolecular Structure (6
units). Lecture, 5 hours. Prerequisites:
Chemistry: 110A, 153A, 153B, 153C, 156, or equivalent. Chemical
and physical properties of proteins and nucleic acids. Structure,
cloning, and analysis of DNA; biosynthesis and processing of RNA;
biosynthesis, purification, structure, and analysis of proteins;
correlation of structure and biological properties. Letter grading.
(Fall)
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M257. MM Pharm Introduction
to Toxicology (4 units). Same as Pathology M257.
Requisite: course 241 or consent of instructor. Biochemical and
systemic toxicology, basic mechanisms of toxicology, and interaction
of toxic agents with specific organ systems. S/U or letter grading.
(Quarter TBD).
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M258. MM Pharm Pathologic Changes in Toxicology (4 units).
Designed to give students experience in learning normal
histology of tissues which are major targets of toxin and the range
of pathologic changes that occur in these tissues (liver, bladder,
lung, kidney, nervous system, and vascular system) (Quarter TBD).
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M267 A & B. Biol Chem Cell Structure, Signaling and
Development (6 units). Lecture, and lab, five hours.
Requisites: Chemistry 153A, 153B, 153C. Recommended: course CM153G.
Cell cycle regulation; chromosomes and DNA repair; protein trafficking
and endocytosis; extracellular matrix, cell to cell communication
and signal transduction; cell transformation and apoptosis; molecular
aspects of development, differentiation, and cancer. A & B are
taken concurrently. Letter grading.
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M276. MM Pharm Advanced Topics in Animal
Virus/Host Interaction (4 units). Same as MIMG CM276 and
MCDB CM 258. Lecture, four hours; discussion, one hour.
Requisites: Chemistry 153B or Microbiology 102 or MCDB 144.
Recent developments in fields of interaction of hosts with
animal viruses. Emphasis on molecular and cellular approaches
to understand host/virus interaction at level of entry, replication,
assembly and morphogenesis, as well as host defense and viral pathogenesis.
S/U or letter grade.
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287. MM Pharm Business of Science
(2 units). This course introduces students to principles
of business and entrepreneurship in technology sectors. The
objective is to provide students with the basic business skills
and knowledge required to effectively perform in a commercial environment
and within an academic environment that is increasingly involved
in industry partnerships. (Fall)
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288. MM Pharm Gene Therapy (4
units). Lecture three hours; discussion, one hour.
Introduction to basic concepts of gene therapy, wherein treatment
of human disease is based on transfer of genetic material into an
individual. Discussion of molecular basis of disease, gene delivery
vectors, and animal models. Letter grading. (Spring)
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291. MM Pharm Special Topics in Pharmacology (2
to 4 units). Examination in depth of topics of current
importance in pharmacology. Emphasis on recent contributions of
special interest to advanced Ph.D. candidates and faculty. S/U or
letter grading. (Fall, Winter)
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293. MM Pharm Nitric Oxide Chemistry, Biochemistry and
Physiology (2-4 units). Lecture, two or four hours. This
course covers the basic chemistry, biochemistry and physiology of
nitric oxide and related species. There will be an emphasis on understanding
the novel mechanisms of nitrogen oxide function as both a physiological
and pathophysiological agent/messenger. Letter grading. (Winter)
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297/298. MM Pharm Seminar: Current Topics (2
units) . Same as Molecular Biology 297/298. Limited
to Pharmacology majors, ACCESS program students, and Interdepartmental
Molecular Biology Ph.D. program students. Students conduct or participate
in discussions on assigned topics. S/U or letter grading. (Winter)
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375. MM Pharm Teaching Apprentice Practicum
(1 to 4 units). Pharmacology or ACCESS majors.
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596. MM Pharm Directed Individual Research in Pharmacology
(4 to 12 units) . Every
quarter after completing rotations.
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599. MM Pharm Research for and Preparation of Ph.D. Dissertation
(4 to 12 units). Every
quarter after passing the qualifying exam and advancing to candidacy.
Undergraduate Courses
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110A MM Pharm Drugs: Mechanisms, Uses, and Misuses (4units
). Lecture & discussion. Requisites: Chemistry
15, Life Sciences 2, 3. Introduction to pharmacology for undergraduate
students.
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199. MM Pharm Independent Studies (2 to 8 units ).
Prerequisites: consent of instructor and department
chair. Special studies in Pharmacology. May include reading assignments
and laboratory work. Designed for the training of students.