Cameron Gundersen, Ph.D.

Positions & Affiliations:

Professor Emeritus, Molecular and Medical Pharmacology

Research Description:

My research focuses on events at nerve endings that are essential for the exocytotic release of neurotransmitter. Abundant progress has implicated several proteins as essential contributors to the cascade of events that culminate in the fusion of the synaptic vesicle membrane with the presynaptic plasma membrane. But, it remains unclear how these proteins cooperate to drive the ultrafast, quantal secretion of neurotransmitter. I am continuing collaborations with several groups to pursue answers that will lead to a better understanding of this process.

1. Gundersen, C.B. (2020) Cysteine String Proteins. Progress in Neurobiology 188:101758.

2. Gundersen, C.B. (2020) Fast, synchronous neurotransmitter release: Past, present and future. Neuroscience 439:22-27.

3. Ruchala P, Waring AJ, Cilluffo M, Whitelegge JP, Gundersen, C.B. (2019) Insights into the structure and molecular topography of the fatty acylated domain of synaptotagmin 1. Biochimica Biophysica Acta 1861: 677-684.

Bio:

Ph.D. in Neuroscience (UCLA); Postdoctoral Researcher (UCLA); Postdoctoral Researcher (University College London)