Shiyue (Sabrina) Yang
I graduated from the University of North Carolina at Chapel Hill in 2022 with highest honors and highest distinction in Biology and Chemistry. I started my research experience as a freshman in the Yue Xiong lab at UNC, where I eventually finished my undergraduate honor thesis on the biophysical, biochemical, and cellular mechanisms of vitamin C as a novel activator of TET2 DNA Dioxygenase to suppress tumor growth. Meanwhile, I worked with the Qi Zhang lab at UNC to study the structural basis of nucleosome-dependent cGAS regulation that constitutes innate tumor-immunity. My brief internship at Inventis Bio to assist pharmaceutical development of K-Ras inhibitors helped identify my current interest in translational cancer research, which resides in extending the understanding of tumorigenesis mechanisms. As a new graduate student at UCLA MMP, I am excited to explore more clinically relevant topics in cancer cell signalling and tumor-immunology. Outside of the lab, I enjoy staying indoors for cooking and making crafts, as well as spending time outdoors for hiking, fishing, and photography.